Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769343 | 0.82 | KMT2A (0.56) | KMT2ATDP1MEN1APEX1L3MBTL1 | |
| SCHEMBL22960861 | 0.80 | KMT2A (0.54) | KMT2ATDP1MEN1APEX1L3MBTL1 | |
| SCHEMBL19359470 | 0.80 | CRBN (0.56) | KMT2ATDP1MEN1APEX1L3MBTL1 | |
| SCHEMBL31073664 | 0.79 | KMT2A (0.61) | KMT2ATDP1MEN1APEX1L3MBTL1 | |
| SCHEMBL20812624 | 0.78 | CRBN (0.57) | KMT2ATDP1MEN1APEX1L3MBTL1 | |
| SCHEMBL5579426 | 0.73 | ALDH1A1 (0.53) | KMT2ATDP1MEN1APEX1L3MBTL1 | |
| SCHEMBL20812349 | 0.73 | CRBN (0.57) | KMT2ATDP1MEN1APEX1L3MBTL1 | |
| SCHEMBL27123348 | 0.73 | ALDH1A1 (0.53) | KMT2ATDP1MEN1APEX1L3MBTL1 | |
| SCHEMBL2301305 | 0.71 | ALDH1A1 (0.71) | KMT2ATDP1MEN1APEX1L3MBTL1 | |
| SCHEMBL19359372 | 0.71 | CRBN (0.73) | KMT2ATDP1MEN1APEX1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641007-A | Direct reprogramming of human somatic cells into selected (predetermined) differentiated cells using functionalized nanoparticles | 斯特姆詹尼克斯公司 | 2019-04-16 | — | — | CN | disclosed |