Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGFR | P43088 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29291079 | 0.81 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL29291073 | 0.74 | LMNA (0.40) | ALDH1A1LMNARAB9ASMN1; SMN2HTT | |
| SCHEMBL29291076 | 0.72 | LMNA (0.44) | ALDH1A1LMNARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL29291085 | 0.70 | ALDH1A1 (0.59) | ALDH1A1LMNARAB9ASMN1; SMN2HTT | |
| SCHEMBL29291078 | 0.70 | AKT1 (0.36) | LMNARAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL28147793 | 0.66 | MAPK1 (0.51) | LMNARAB9ASMN1; SMN2HTTMAPT | |
| SCHEMBL155790 | 0.65 | IDO1 (0.60) | LMNASMN1; SMN2HTTKDM4EIDO1 | |
| SCHEMBL2097653 | 0.65 | IDO1 (0.65) | ALDH1A1LMNARAB9ASMN1; SMN2HTT | |
| SCHEMBL15497186 | 0.64 | LMNA (0.67) | ALDH1A1LMNARAB9ASMN1; SMN2HTT | |
| SCHEMBL1625791 | 0.64 | IDO1 (0.54) | ALDH1A1HTTMAPTIDO1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705054-A | The thioether sulfone compound and its preparation method and application of one class preventing and control Banana Root nematode | 贵州大学 | 2019-05-03 | — | — | CN | claimed |
| CN-109705054-A | The thioether sulfone compound and its preparation method and application of one class preventing and control Banana Root nematode | 贵州大学 | 2019-05-03 | — | — | CN | disclosed |