Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29291084 | 0.80 | ALDH1A1 (0.55) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL3731624 | 0.75 | ALDH1A1 (1.00) | ALDH1A1LMNARAB9ASMN1; SMN2HTT | |
| SCHEMBL29291075 | 0.70 | ALDH1A1 (0.47) | ALDH1A1LMNARAB9ASMN1; SMN2HTT | |
| SCHEMBL29291083 | 0.70 | LMNA (0.61) | ALDH1A1LMNARAB9ASMN1; SMN2MAPT | |
| SCHEMBL27984899 | 0.69 | PTGER1 (0.47) | ALDH1A1LMNARAB9ASMN1; SMN2HTT | |
| SCHEMBL7993600 | 0.68 | CA2 (0.43) | ALDH1A1 | |
| SCHEMBL29291087 | 0.68 | PTGS2 (0.45) | ALDH1A1LMNASMN1; SMN2MAPTGAA | |
| SCHEMBL3467900 | 0.67 | ALDH1A1 (0.52) | ALDH1A1LMNARAB9ASMN1; SMN2HTT | |
| SCHEMBL2097653 | 0.67 | IDO1 (0.65) | ALDH1A1LMNARAB9ASMN1; SMN2HTT | |
| SCHEMBL6011808 | 0.67 | IDO1 (0.50) | ALDH1A1SMN1; SMN2HTTMAPTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705054-A | The thioether sulfone compound and its preparation method and application of one class preventing and control Banana Root nematode | 贵州大学 | 2019-05-03 | — | — | CN | claimed |
| CN-109705054-A | The thioether sulfone compound and its preparation method and application of one class preventing and control Banana Root nematode | 贵州大学 | 2019-05-03 | — | — | CN | disclosed |