Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 1/20 | 0.68 |
| ▸ | AURKA | O14965 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.59 |
| ▸ | CSF1R | P07333 | 1/20 | 0.59 |
| ▸ | FLT1 | P17948 | 1/20 | 0.59 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.59 |
| ▸ | TYK2 | P29597 | 1/20 | 0.59 |
| ▸ | AKT1 | P31749 | 1/20 | 0.59 |
| ▸ | FLT4 | P35916 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | FLT3 | P36888 | 1/20 | 0.59 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.59 |
| ▸ | STK3 | Q13188 | 1/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.59 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.59 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.59 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.59 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29291558 | 0.89 | FLT3 (0.67) | DHPSAURKAROCK2ERBB2CSF1R | |
| SCHEMBL4619725 | 0.79 | HDAC8 (0.60) | TRPV1NAMPTNPC1CYP1A2HPGD | |
| SCHEMBL14051580 | 0.74 | NPC1 (0.73) | ROCK2RPS6KB1ROCK1SGK2NPC1 | |
| SCHEMBL7303163 | 0.73 | HDAC3 (0.86) | TRPV1NAMPTNPC1LMNACYP1A2 | |
| SCHEMBL12044572 | 0.72 | PTPN1 (0.70) | TRPV1NPC1RAB9AHDAC3HDAC11 | |
| SCHEMBL29291565 | 0.72 | CIT (0.63) | ROCK2TRPV1 | |
| SCHEMBL3875835 | 0.72 | TRPV1 (0.76) | TRPV1NAMPT | |
| SCHEMBL28237558 | 0.71 | METAP2 (0.66) | AURKAROCK2ERBB2CSF1RFLT1 | |
| SCHEMBL2380299 | 0.71 | ABL1 (0.52) | AURKAROCK2ERBB2CSF1RFLT1 | |
| SCHEMBL3873327 | 0.71 | TRPV1 (0.66) | KDRTRPV1NAMPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735859-A | Kinase inhibitor | 安徽医科大学 | 2021-12-03 | — | — | CN | disclosed |