Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 5/20 | 0.67 |
| ▸ | KDR | P35968 | 3/20 | 0.67 |
| ▸ | AURKA | O14965 | 1/20 | 0.67 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.67 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.67 |
| ▸ | CSF1R | P07333 | 1/20 | 0.67 |
| ▸ | FLT1 | P17948 | 1/20 | 0.67 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.67 |
| ▸ | TYK2 | P29597 | 1/20 | 0.67 |
| ▸ | AKT1 | P31749 | 1/20 | 0.67 |
| ▸ | FLT4 | P35916 | 1/20 | 0.67 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.67 |
| ▸ | STK3 | Q13188 | 1/20 | 0.67 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.67 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.67 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.67 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.67 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.67 |
| ▸ | DHPS | P49366 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29291528 | 0.89 | DHPS (0.68) | FLT3KDRAURKAROCK2ERBB2 | |
| SCHEMBL4619469 | 0.78 | HDAC8 (0.63) | NPC1RAB9AHPGDNAMPTTRPV1 | |
| SCHEMBL4092755 | 0.78 | KDR (0.74) | FLT3KDRAURKAROCK2ERBB2 | |
| SCHEMBL30501550 | 0.78 | KDR (0.74) | FLT3KDRAURKAROCK2ERBB2 | |
| SCHEMBL29291563 | 0.74 | TRPV1 (0.54) | NPC1RAB9AHPGDNAMPTTRPV1 | |
| SCHEMBL17066707 | 0.73 | RAB9A (0.88) | NPC1RAB9ALMNANAMPTTRPV1 | |
| SCHEMBL25970267 | 0.73 | RAB9A (0.88) | NPC1RAB9ALMNANAMPTTRPV1 | |
| SCHEMBL15214314 | 0.73 | RAB9A (0.88) | NPC1RAB9ALMNANAMPTTRPV1 | |
| SCHEMBL25491824 | 0.73 | RAB9A (0.88) | NPC1RAB9ALMNANAMPTTRPV1 | |
| SCHEMBL5415932 | 0.73 | MAOB (0.69) | ROCK2RPS6KB1ROCK1SGK2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735859-A | Kinase inhibitor | 安徽医科大学 | 2021-12-03 | — | — | CN | disclosed |