Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29294901 | 0.90 | NLRP3 (0.45) | NLRP3PDE3BPDE3AKMT2AIRAK4 | |
| SCHEMBL29294075 | 0.88 | NLRP3 (0.49) | NLRP3PDE3BPDE3AKMT2AIRAK4 | |
| SCHEMBL29295113 | 0.86 | NLRP3 (0.50) | NLRP3PDE3BPDE3AKMT2APIK3CA | |
| SCHEMBL29294905 | 0.85 | PDE3B (0.39) | NLRP3PDE3BPDE3AKMT2AIRAK4 | |
| SCHEMBL31367978 | 0.83 | PDE3B (0.38) | PDE3BPDE3AKMT2AIRAK4PIK3CA | |
| SCHEMBL29294065 | 0.82 | NLRP3 (0.53) | NLRP3KMT2AIRAK4TSHRALDH1A1 | |
| SCHEMBL29295243 | 0.79 | NLRP3 (0.50) | NLRP3KMT2AIRAK4TSHRALDH1A1 | |
| SCHEMBL29294923 | 0.79 | NLRP3 (0.42) | NLRP3PDE3BPDE3AKMT2ATSHR | |
| SCHEMBL29295109 | 0.79 | NLRP3 (0.52) | NLRP3KMT2AIRAK4TSHRALDH1A1 | |
| SCHEMBL29294899 | 0.79 | NLRP3 (0.58) | NLRP3PDE3BPDE3AKMT2APIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397663-A1 | 6-AMINOPYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2024-07-10 | — | — | EP | disclosed |