Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA3 | P07451 | 2/20 | 0.53 |
| ▸ | CA5A | P35218 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926491 | 0.81 | KCNMA1 (0.50) | KDM4EALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL2924487 | 0.81 | KDM4E (0.52) | CA12CA1CA2CA3CA5A | |
| SCHEMBL7498157 | 0.81 | CA12 (0.41) | CA12CA1CA2CA3CA5A | |
| SCHEMBL7500797 | 0.81 | KCNMA1 (0.43) | CA12CA1CA2CA3CA5A | |
| SCHEMBL2933540 | 0.79 | KCNMA1 (0.67) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5470345 | 0.76 | RAB9A (0.58) | CA1CA2MAOAKDM4EALDH1A1 | |
| SCHEMBL17284920 | 0.76 | KMT2A (0.68) | MAOAKDM4EALDH1A1L3MBTL1RAB9A | |
| SCHEMBL11733627 | 0.75 | KDM4E (0.60) | KDM4EALDH1A1L3MBTL1RAB9APOLB | |
| SCHEMBL7505833 | 0.74 | PBRM1 (0.44) | MAOAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7503751 | 0.74 | CA12 (0.42) | CA12CA1CA2CA3CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812177-B2 | Potassium channel opener having benzofuroindole skeleton | ANYGEN CO., LTD. (KR) | 2010-10-12 | — | — | US | disclosed |
| EP-1861092-B1 | POTASSIUM CHANNEL OPENER HAVING BENZOFUROINDOLE SKELETON | ANYGEN CO LTD (KR) | 2010-09-15 | — | — | EP | disclosed |
| EP-1861092-A4 | POTASSIUM CHANNEL OPENER HAVING BENZOFUROINDOLE SKELETON | ANYGEN CO LTD (KR) | 2009-04-15 | — | — | EP | disclosed |
| US-20080194837-A1 | Potassium Channel Opener Having Benzofuroindole Skeleton | ANYGEN CO., LTD. (KR) | 2008-08-14 | — | — | US | disclosed |
| EP-1861092-A1 | POTASSIUM CHANNEL OPENER HAVING BENZOFUROINDOLE SKELETON | Anygen Co., Ltd. (KR) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006096030-A1 | POTASSIUM CHANNEL OPENER HAVING BENZOFUROINDOLE SKELETON | ANYGEN CO., LTD. (KR) | 2006-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194837-A1 | Potassium Channel Opener Having Benzofuroindole Skeleton | KCNJ2, KCNN3, KCNH2 | CA12 2649/4885CA1 1446/4885CA2 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.