Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29295189 | 0.73 | NLRP3 (0.56) | HPGDMAPK1NPSR1KMT2ATSHR | |
| SCHEMBL29294062 | 0.73 | NLRP3 (0.69) | HPGDMAPK1NPSR1KMT2ATSHR | |
| SCHEMBL29295027 | 0.72 | NLRP3 (0.52) | HPGDMAPK1NPSR1KMT2ATSHR | |
| SCHEMBL29294699 | 0.72 | NLRP3 (0.57) | HPGDMAPK1NPSR1KMT2ATSHR | |
| SCHEMBL29294230 | 0.72 | KMT2A (0.39) | HPGDMAPK1NPSR1KMT2ATSHR | |
| SCHEMBL29294427 | 0.71 | KMT2A (0.47) | KMT2ATSHRMEN1HSD17B10ALDH1A1 | |
| SCHEMBL29295247 | 0.71 | NLRP3 (0.54) | HPGDMAPK1NPSR1KMT2ATSHR | |
| SCHEMBL29294873 | 0.70 | NLRP3 (0.56) | HPGDMAPK1NPSR1KMT2ATSHR | |
| SCHEMBL29294222 | 0.70 | NLRP3 (0.53) | HPGDMAPK1NPSR1KMT2ATSHR | |
| SCHEMBL30307855 | 0.69 | TSHR (0.48) | HPGDMAPK1NPSR1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397663-A1 | 6-AMINOPYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2024-07-10 | — | — | EP | disclosed |