Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 2/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2420509 | 0.72 | HTR3A (0.70) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL27167464 | 0.70 | SMN1; SMN2 (0.55) | TSHRALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL30054892 | 0.70 | SMN1; SMN2 (0.55) | TSHRALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL15693122 | 0.69 | KMT2A (0.48) | TSHRALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL29294223 | 0.69 | HPGD (0.43) | TSHRALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL4981345 | 0.69 | TSHR (0.45) | TSHRALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL29295027 | 0.68 | NLRP3 (0.52) | TSHRALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL29294699 | 0.68 | NLRP3 (0.57) | TSHRALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL11679829 | 0.68 | TSHR (0.54) | TSHRALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL4985818 | 0.68 | SMN1; SMN2 (0.44) | TSHRALDH1A1KMT2AMEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023032987-A1 | 6-AMINOPYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | 日本たばこ産業株式会社 | 2023-03-09 | — | — | WO | disclosed |