Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29294455 | 0.90 | ADORA3 (0.48) | KMT2AADORA3NLRP3HTR3APOLB | |
| SCHEMBL29294201 | 0.90 | ADORA3 (0.48) | ADORA3NLRP3ALDH1A1HTR3APOLB | |
| SCHEMBL29294465 | 0.89 | ADORA3 (0.47) | ADORA3NLRP3TSHRHSD17B10ALDH1A1 | |
| SCHEMBL29295027 | 0.88 | NLRP3 (0.52) | KMT2ANLRP3TSHRMEN1HSD17B10 | |
| SCHEMBL29294571 | 0.87 | NLRP3 (0.46) | KMT2ANLRP3TSHRMEN1HSD17B10 | |
| SCHEMBL29294222 | 0.85 | NLRP3 (0.53) | KMT2ANLRP3TSHRMEN1HSD17B10 | |
| SCHEMBL29294871 | 0.85 | NLRP3 (0.44) | KMT2ANLRP3TSHRMEN1HSD17B10 | |
| SCHEMBL29294477 | 0.84 | KMT2A (0.45) | KMT2ANLRP3TSHRAPAF1CDC25B | |
| SCHEMBL29294459 | 0.84 | PIK3C3 (0.44) | ADORA3NLRP3IRAK4 | |
| SCHEMBL29295234 | 0.84 | KMT2A (0.45) | KMT2ANLRP3TSHRMEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397663-A1 | 6-AMINOPYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2024-07-10 | — | — | EP | disclosed |