Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29294872 | 0.96 | NLRP3 (0.42) | NLRP3HTR3AHRH4AKR1C3KMT2A | |
| SCHEMBL29294695 | 0.91 | HRH4 (0.47) | NLRP3HTR3AHRH4NPC1RAB9A | |
| SCHEMBL29294571 | 0.90 | NLRP3 (0.46) | NLRP3KMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL29294222 | 0.88 | NLRP3 (0.53) | NLRP3KMT2AMEN1RAB9ATSHR | |
| SCHEMBL29295097 | 0.87 | NLRP3 (0.47) | NLRP3HTR3AHRH4KMT2AMEN1 | |
| SCHEMBL29294873 | 0.87 | NLRP3 (0.56) | NLRP3HTR3AHRH4KMT2AMEN1 | |
| SCHEMBL29294427 | 0.85 | KMT2A (0.47) | NLRP3HTR3AAKR1C3KMT2AMEN1 | |
| SCHEMBL29294902 | 0.85 | HTR3A (0.40) | NLRP3HTR3AHRH4KMT2AHSD17B10 | |
| SCHEMBL29295046 | 0.85 | NLRP3 (0.42) | NLRP3KMT2AMEN1RAB9ATSHR | |
| SCHEMBL29295134 | 0.85 | KMT2A (0.42) | NLRP3HTR3AHRH4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397663-A1 | 6-AMINOPYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2024-07-10 | — | — | EP | disclosed |