Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | MAT2A | P31153 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29294872 | 0.91 | NLRP3 (0.42) | HRH4HTR3AADORA1HCRTR1HCRTR2 | |
| SCHEMBL29294871 | 0.91 | NLRP3 (0.44) | HRH4HTR3AHCRTR1HCRTR2NLRP3 | |
| SCHEMBL29294529 | 0.89 | NLRP3 (0.43) | HRH4HTR3AADORA1HCRTR1HCRTR2 | |
| SCHEMBL29294782 | 0.89 | HRH4 (0.46) | HRH4HTR3AADORA1HCRTR1HCRTR2 | |
| SCHEMBL29294703 | 0.87 | HTR3A (0.44) | HRH4HTR3AADORA1HCRTR1HCRTR2 | |
| SCHEMBL29294585 | 0.87 | NLRP3 (0.51) | HRH4HTR3AADORA1HCRTR1HCRTR2 | |
| SCHEMBL29294952 | 0.87 | HTR3A (0.44) | HRH4HTR3AADORA1HCRTR1HCRTR2 | |
| SCHEMBL29294755 | 0.85 | KDM4E (0.47) | HTR3ANLRP3RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL29294664 | 0.85 | KDM4E (0.43) | HRH4HTR3ANLRP3RAB9ASMN1; SMN2 | |
| SCHEMBL29294674 | 0.85 | MGLL (0.44) | HRH4HTR3AADORA1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397663-A1 | 6-AMINOPYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2024-07-10 | — | — | EP | disclosed |