Dibrompropamidine

Dibrompropamidine

SCHEMBL292947

N=C(N)c1ccc(OCCCOc2ccc(C(=N)N)cc2Br)c(Br)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 1.00
PLAU P00749 1/20 1.00
ST14 Q9Y5Y6 1/20 1.00
PRSS1 P07477 10/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibrompropamidine SCHEMBL29709297 1.00 F2 (1.00) F2PLAUST14PRSS1
Dibrompropamidine SCHEMBL21083095 0.98 F2 (0.97) F2PLAUST14PRSS1
SCHEMBL597315 0.95 F2 (0.90) F2PLAUST14PRSS1
SCHEMBL14599538 0.95 F2 (0.90) F2PLAUST14PRSS1
Dibrompropamidine SCHEMBL28086367 0.92 F2 (0.85) F2PLAUST14PRSS1
SCHEMBL16360744 0.89 F2 (0.79) F2PLAUST14PRSS1
SCHEMBL22824438 0.88 F2 (0.78) F2PLAUST14PRSS1
SCHEMBL1428334 0.88 F2 (0.78) F2PLAUST14PRSS1
SCHEMBL16450812 0.86 F2 (0.75) F2PLAUST14PRSS1
Dibrompropamidine SCHEMBL2471251 0.85 F2 (0.72) F2PLAUST14PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1964 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091119-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA CELLIS AG (CH) 2026-04-02 US claimed
US-20250346910-A1 METHODS AND COMPOSITIONS TO PREVENT MICROBIAL INFECTION COMMENSE BIO INC (US) 2025-11-13 US claimed
EP-4637829-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF OVARIAN CANCER Cellis Sp. z o.o. ([Ltd.] (PL) 2025-10-29 EP claimed
EP-4587062-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA Cellis AG (CH) 2025-07-23 EP claimed
CN-119907692-A Isolated targeted delivery system for the treatment of gliomas 塞尔丽思股份公司 2025-04-29 CN claimed
US-12274830-B2 Nitric oxide inhalation therapy for infants with bronchiolitis BEYOND AIR LTD (IL) 2025-04-15 US claimed
US-20250075182-A1 CELLULAR TARGETED ACTIVE INGREDIENT DELIVERY SYSTEM CELLIS AG (CH) 2025-03-06 US claimed
WO-2024133541-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF OVARIAN CANCER CELLIS SP. Z O.O. [LTD.] (PL) 2024-06-27 WO claimed
US-20240173512-A1 METHODS FOR POTENTIATING ANTIMICROBIAL AGENTS STREETERVILLE CAPITAL, LLC 2024-05-30 US claimed
EP-3310904-B1 CELLULAR TARGETED ACTIVE INGREDIENT DELIVERY SYSTEM CELLIS AG (CH) 2024-04-03 EP claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
WO-2000030599-A1 SKIN DEODORIZING AND SANITIZING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2000-06-02 WO claimed
EP-0617611-B1 ORAL OSMOTIC DEVICE ALZA CORP (US) 1996-01-31 EP claimed
US-5357636-A Flexible protective medical gloves and methods for their use DRESDNER JR KARL P (US) 1994-10-25 US claimed
EP-0439450-B1 PHARMACEUTICAL COMPOSITION SMITH & NEPHEW plc (GB) 1992-12-23 EP claimed
EP-0439450-A1 PHARMACEUTICAL COMPOSITION. SMITH & NEPHEW ASS (GB) 1991-08-07 EP claimed
WO-1989000850-A1 PHARMACEUTICAL COMPOSITION SMITH & NEPHEW PLC (GB) 1989-02-09 WO claimed
WO-1984004456-A1 IMPROVED COMPOSITIONS FOR TREATING INFECTED BURN WOUNDS UNIV STRATHCLYDE (GB) 1984-11-22 WO claimed
EP-0125858-A1 Improved compositions for treating infected burn wounds University of Strathclyde (GB) 1984-11-21 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091119-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA CD47, TFRC, L1CAM F2 3181/4885PLAU 3740/4885ST14 982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.