Dibrompropamidine

Dibrompropamidine

SCHEMBL29709297

N=C(N)c1ccc(OCCCOc2ccc(C(=N)N)cc2Br)c(Br)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 1.00
PLAU P00749 1/20 1.00
ST14 Q9Y5Y6 1/20 1.00
PRSS1 P07477 10/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibrompropamidine SCHEMBL292947 1.00 F2 (1.00) F2PLAUST14PRSS1
Dibrompropamidine SCHEMBL21083095 0.98 F2 (0.97) F2PLAUST14PRSS1
SCHEMBL597315 0.95 F2 (0.90) F2PLAUST14PRSS1
SCHEMBL14599538 0.95 F2 (0.90) F2PLAUST14PRSS1
Dibrompropamidine SCHEMBL28086367 0.92 F2 (0.85) F2PLAUST14PRSS1
SCHEMBL16360744 0.89 F2 (0.79) F2PLAUST14PRSS1
SCHEMBL22824438 0.88 F2 (0.78) F2PLAUST14PRSS1
SCHEMBL1428334 0.88 F2 (0.78) F2PLAUST14PRSS1
SCHEMBL16450812 0.86 F2 (0.75) F2PLAUST14PRSS1
Dibrompropamidine SCHEMBL2471251 0.85 F2 (0.72) F2PLAUST14PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4694929-A1 METHODS FOR TREATING CORNEAL INJURIES Lin, Sung-Jan (TW) 2026-02-18 EP claimed
WO-2024212857-A1 METHODS FOR TREATING CORNEAL INJURIES LIN SUNG JAN (CN) 2024-10-17 WO claimed
EP-3310904-B1 CELLULAR TARGETED ACTIVE INGREDIENT DELIVERY SYSTEM CELLIS AG (CH) 2024-04-03 EP claimed
EP-4694929-A1 METHODS FOR TREATING CORNEAL INJURIES Lin, Sung-Jan (TW) 2026-02-18 EP disclosed
US-20250367232-A1 HALOGEN TREATMENT OF HEART ATTACK AND ISCHEMIC INJURY HUTCHINSON FRED CANCER RES (US) 2025-12-04 US disclosed
CN-114929340-B Methods and agents for glaucoma 奥夫博医疗创新有限公司 2025-06-10 CN disclosed
CN-113164043-B Compositions and methods for glaucoma 奥夫博医疗创新有限公司 2024-10-22 CN disclosed
WO-2024212857-A1 METHODS FOR TREATING CORNEAL INJURIES LIN SUNG JAN (CN) 2024-10-17 WO disclosed
US-12016880-B2 Halogen treatment of heart attack and ischemic injury FRED HUTCHINSON CANCER CENTER (US) 2024-06-25 US disclosed
EP-3104939-B1 TREATMENT OF HEART ATTACK AND ISCHEMIC INJURY WITH SODIUM IODIDE FRED HUTCHINSON CANCER CENTER (US) 2024-05-01 EP disclosed
US-20240000849-A1 MICROFLUIDIC DEVICE FOR ISOLATING COMPONENTS OF BODILY FLUIDS UNIV CORNELL (US) 2024-01-04 US disclosed
US-11752175-B2 Compositions and methods for glaucoma CORNELL UNIVERSITY (US) 2023-09-12 US disclosed
US-20220313730-A1 HALOGEN TREATMENT OF HEART ATTACK AND ISCHEMIC INJURY FRED HUTCHINSON CANCER CENTER 2022-10-06 US disclosed
US-11400106-B2 Methods for inhibiting microbe growth MCMASTER UNIVERSITY (CA) 2022-08-02 US disclosed
EP-4031244-A1 PROCESSES AND AGENTS FOR GLAUCOMA Aufbau Medical Innovations Limited (IE) 2022-07-27 EP disclosed
US-20220211800-A1 PROCESSES AND AGENTS FOR GLAUCOMA CORNELL UNIVERSITY (US) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220211800-A1 PROCESSES AND AGENTS FOR GLAUCOMA RHOA, PDE6C, EXOSC10 F2 3817/4885PLAU 395/4885ST14 4634/4885
US-11400106-B2 Methods for inhibiting microbe growth MMP8, BPGM, CAPG F2 3617/4885PLAU 593/4885ST14 1734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.