Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.39 |
| ▸ | PDE9A | O76083 | 2/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29294827 | 0.92 | HRH4 (0.42) | KMT2AHTR3AHRH4NLRP3TSHR | |
| SCHEMBL29295102 | 0.89 | NLRP3 (0.43) | KMT2APIK3CAPIK3CBNLRP3ALDH1A1 | |
| SCHEMBL29295231 | 0.86 | KMT2A (0.41) | KMT2AHTR3AHRH4PIK3CAPIK3CB | |
| SCHEMBL29294862 | 0.86 | HRH4 (0.36) | HTR3AHRH4PDE9ANLRP3 | |
| SCHEMBL29294871 | 0.85 | NLRP3 (0.44) | KMT2AHTR3AHRH4PIK3CAPIK3CB | |
| SCHEMBL29294872 | 0.82 | NLRP3 (0.42) | KMT2AHTR3AHRH4NLRP3ALDH1A1 | |
| SCHEMBL29294902 | 0.81 | HTR3A (0.40) | KMT2AHTR3AHRH4PIK3CAPIK3CB | |
| SCHEMBL29295134 | 0.78 | KMT2A (0.42) | KMT2AHTR3AHRH4PIK3CAPIK3CB | |
| SCHEMBL29294952 | 0.78 | HTR3A (0.44) | KMT2AHTR3AHRH4ALDH1A1TSHR | |
| SCHEMBL29294571 | 0.77 | NLRP3 (0.46) | KMT2APIK3CAPIK3CBNLRP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397663-A1 | 6-AMINOPYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2024-07-10 | — | — | EP | disclosed |