Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | PTPRC | P08575 | 1/20 | 0.51 |
| ▸ | PTPRG | P23470 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11715445 | 0.85 | L3MBTL1 (0.53) | L3MBTL1PKMALDH1A1TDP1GAA | |
| SCHEMBL30016479 | 0.85 | PTPRC (0.54) | L3MBTL1PTPRCPTPRGALDH1A1KMT2A | |
| SCHEMBL18769941 | 0.85 | PTPRC (0.54) | L3MBTL1PTPRCPTPRGALDH1A1KMT2A | |
| SCHEMBL30016005 | 0.84 | PTPRC (0.68) | L3MBTL1PTPRCPTPRGALDH1A1GAA | |
| SCHEMBL11719632 | 0.84 | L3MBTL1 (0.52) | L3MBTL1PKMPTPRCALDH1A1TDP1 | |
| SCHEMBL11712860 | 0.84 | L3MBTL1 (0.52) | L3MBTL1PKMALDH1A1TDP1GAA | |
| SCHEMBL8628655 | 0.83 | POLB (0.65) | L3MBTL1PKMPTPRGALDH1A1TDP1 | |
| SCHEMBL28298585 | 0.83 | L3MBTL1 (0.51) | L3MBTL1PKMALDH1A1TDP1GAA | |
| SCHEMBL28109773 | 0.82 | KMT2A (0.64) | L3MBTL1PTPRCPTPRGALDH1A1KMT2A | |
| SCHEMBL11714137 | 0.82 | L3MBTL1 (0.50) | L3MBTL1PKMALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226115-A1 | AXL INHIBITOR COMPOUNDS | ARCUS BIOSCIENCES, INC. | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226115-A1 | AXL INHIBITOR COMPOUNDS | AXL, BTK, MERTK | L3MBTL1 1171/4885PKM 1412/4885PTPRC 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.