Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 3/20 | 0.68 |
| ▸ | PTPRG | P23470 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 3/20 | 0.44 |
| ▸ | CA6 | P23280 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820877 | 0.91 | PTPRG (0.69) | PTPRCPTPRGKMT2AALDH1A1MEN1 | |
| SCHEMBL18769941 | 0.88 | PTPRC (0.54) | PTPRCPTPRGKMT2AALDH1A1MEN1 | |
| SCHEMBL30016479 | 0.88 | PTPRC (0.54) | PTPRCPTPRGKMT2AALDH1A1MEN1 | |
| SCHEMBL28109773 | 0.88 | KMT2A (0.64) | PTPRCPTPRGKMT2AALDH1A1MEN1 | |
| SCHEMBL11817650 | 0.87 | PTPRG (0.76) | PTPRCPTPRGKMT2AMEN1NPC1 | |
| SCHEMBL17927526 | 0.84 | PTPRC (0.51) | PTPRCPTPRGKMT2AALDH1A1MEN1 | |
| SCHEMBL29295506 | 0.84 | L3MBTL1 (0.52) | PTPRCPTPRGKMT2AALDH1A1MEN1 | |
| SCHEMBL11567962 | 0.83 | PTPRG (0.51) | PTPRCPTPRGKMT2AALDH1A1MEN1 | |
| SCHEMBL17927618 | 0.82 | PTPRC (0.49) | PTPRCPTPRGKMT2AALDH1A1MEN1 | |
| SCHEMBL1901284 | 0.80 | PTPRG (0.67) | PTPRCPTPRGKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313967-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |