Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | WNT1 | P04628 | 2/20 | 0.30 |
| ▸ | GSK3B | P49841 | 2/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12384237 | 0.83 | SLC18A3 (0.34) | SLC18A3WNT1GSK3BDYRK1A | |
| SCHEMBL12425961 | 0.80 | SIGMAR1 (0.42) | LMNA | |
| Hydrochloric Acid SCHEMBL2291615 | 0.77 | GNAI3 (0.44) | SLC18A3 | |
| SCHEMBL12166745 | 0.75 | TSHR (0.41) | LMNAGAA | |
| SCHEMBL14498527 | 0.74 | — | — | |
| SCHEMBL23740831 | 0.74 | WNT1 (0.31) | WNT1GSK3BDYRK1A | |
| SCHEMBL14498532 | 0.72 | MEN1 (0.50) | LMNA | |
| SCHEMBL29602162 | 0.72 | MEN1 (0.50) | LMNA | |
| SCHEMBL15495015 | 0.70 | GAA (0.41) | LMNAGAA | |
| SCHEMBL14498621 | 0.70 | GAA (0.41) | LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226113-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226113-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | TP53, HRAS, KRAS | LMNA 2568/4885SLC18A3 4053/4885WNT1 909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.