Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | JAK1 | P23458 | 2/20 | 0.41 |
| ▸ | TYK2 | P29597 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20084360 | 0.89 | JAK2 (0.43) | JAK2JAK1TYK2TRPV4RORC | |
| SCHEMBL29296543 | 0.84 | JAK2 (0.39) | JAK2JAK1TYK2TRPV4RORC | |
| SCHEMBL23388245 | 0.79 | JAK2 (0.39) | JAK2JAK1TYK2RORCHCRTR1 | |
| SCHEMBL568039 | 0.78 | JAK2 (0.38) | JAK2JAK1TYK2TRPV4CLK4 | |
| SCHEMBL7213518 | 0.75 | CA1 (0.42) | JAK2JAK1TYK2CLK4 | |
| SCHEMBL15970403 | 0.75 | TRPV4 (0.43) | JAK2JAK1TYK2TRPV4CLK4 | |
| SCHEMBL22954458 | 0.74 | JAK2 (0.43) | JAK2JAK1TYK2TRPV4CLK4 | |
| SCHEMBL5078527 | 0.73 | RAD51 (0.46) | JAK2JAK1TYK2TRPV4CLK4 | |
| SCHEMBL5078530 | 0.73 | KDM4C (0.36) | JAK2JAK1TYK2TRPV4CLK4 | |
| Hydrochloric Acid SCHEMBL28146131 | 0.73 | KDM4C (0.36) | JAK2JAK1TYK2TRPV4CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228495-A1 | Tricyclic Inhibitors of Influenza Virus Endonuclease | STANFORD RES INST INT (US) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228495-A1 | Tricyclic Inhibitors of Influenza Virus Endonuclease | RNASEH1, RNASEL, DNASE1 | JAK2 3919/4885JAK1 3191/4885TYK2 4599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.