Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29299613 | 0.95 | ALDH1A1 (0.46) | ALDH1A1CASP2LMNAPKMKMT2A | |
| SCHEMBL19239840 | 0.91 | NAMPT (0.45) | ALDH1A1CASP2LMNAPKMKMT2A | |
| SCHEMBL26818740 | 0.90 | CASP2 (0.44) | ALDH1A1CASP2LMNAPKMKMT2A | |
| SCHEMBL23320103 | 0.90 | NAMPT (0.47) | ALDH1A1CASP2LMNAPKMKMT2A | |
| SCHEMBL23320102 | 0.90 | NAMPT (0.47) | ALDH1A1CASP2LMNAPKMKMT2A | |
| SCHEMBL23319056 | 0.90 | NAMPT (0.47) | ALDH1A1CASP2LMNAPKMKMT2A | |
| SCHEMBL26700781 | 0.90 | NAMPT (0.47) | ALDH1A1CASP2LMNAPKMKMT2A | |
| SCHEMBL24934996 | 0.89 | LMNA (0.45) | ALDH1A1CASP2LMNAPKMKMT2A | |
| SCHEMBL15160690 | 0.87 | ALDH1A1 (0.50) | ALDH1A1CASP2LMNAPKMKMT2A | |
| SCHEMBL19880188 | 0.87 | CASP2 (0.52) | ALDH1A1CASP2KMT2AMEN1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226343-A1 | NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF | RADIONETICS ONCOLOGY, INC. | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226343-A1 | NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF | NPY1R, NPY2R, NPY4R | ALDH1A1 3906/4885CASP2 3823/4885LMNA 3809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.