Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 11/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29300481 | 0.87 | GNAI3 (0.43) | TP53SMN1; SMN2FOLH1SIGMAR1HTR7 | |
| SCHEMBL29299819 | 0.87 | FOLH1 (0.51) | TP53SMN1; SMN2NAMPTFOLH1 | |
| SCHEMBL29299828 | 0.87 | FOLH1 (0.48) | TP53SMN1; SMN2NAMPTFOLH1ALDH1A1 | |
| SCHEMBL29300569 | 0.87 | HTR7 (0.39) | TP53SMN1; SMN2NAMPTALDH1A1SIGMAR1 | |
| SCHEMBL29299679 | 0.86 | ALDH1A1 (0.45) | TP53SMN1; SMN2NAMPTFOLH1ALDH1A1 | |
| SCHEMBL254152 | 0.84 | SMN1; SMN2 (0.48) | TP53SMN1; SMN2FOLH1ALDH1A1SIGMAR1 | |
| SCHEMBL29299673 | 0.83 | FOLH1 (0.45) | TP53SMN1; SMN2NAMPTFOLH1ALDH1A1 | |
| SCHEMBL23824133 | 0.83 | SMN1; SMN2 (0.49) | TP53SMN1; SMN2FOLH1ALDH1A1SIGMAR1 | |
| SCHEMBL29299601 | 0.82 | HTR7 (0.41) | TP53SMN1; SMN2NAMPTALDH1A1SIGMAR1 | |
| SCHEMBL29299829 | 0.82 | SMN1; SMN2 (0.46) | TP53SMN1; SMN2NAMPTFOLH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226343-A1 | NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF | RADIONETICS ONCOLOGY, INC. | 2024-07-11 | — | — | US | disclosed |
| US-20240226343-A1 | NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF | RADIONETICS ONCOLOGY, INC. | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226343-A1 | NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF | NPY1R, NPY2R, NPY4R | TP53 517/4885SMN1; SMN2 3725/4885NAMPT 1746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.