Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23675573 | 0.80 | ALDH1A1 (0.33) | — | |
| SCHEMBL19540992 | 0.80 | ALDH1A1 (0.33) | — | |
| SCHEMBL23675571 | 0.80 | ALDH1A1 (0.33) | — | |
| SCHEMBL28037383 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2BCHEACHECHRM3EPHX1 | |
| SCHEMBL12188159 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2EPHX1HRH3HTR2AHTR2C | |
| SCHEMBL3230353 | 0.74 | LMNA (0.46) | EPHX1 | |
| SCHEMBL27268258 | 0.73 | NCF1 (0.43) | SMN1; SMN2CHRM3HRH3HTR2AHTR2C | |
| SCHEMBL26331479 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2BCHEACHECHRM3EPHX1 | |
| SCHEMBL28647347 | 0.72 | ESR1 (0.31) | — | |
| SCHEMBL22309872 | 0.72 | SMN1; SMN2 (0.39) | SMN1; SMN2EPHX1HRH3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148060-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |