Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31057273 | 0.86 | MAPK1 (0.39) | SMYD2BACE1CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL31057375 | 0.82 | SMYD2 (0.38) | SMYD2BACE1CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL15647859 | 0.80 | BCHE (0.39) | SMYD2BACE1CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL15271685 | 0.79 | RORC (0.41) | BACE1HTT | |
| SCHEMBL1487117 | 0.76 | BACE1 (0.35) | SMYD2BACE1CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL14461324 | 0.75 | BACE1 (0.43) | SMYD2BACE1CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL740258 | 0.75 | ACHE (0.46) | BACE1CYP3A4SMN1; SMN2 | |
| SCHEMBL517028 | 0.74 | RBP4 (0.38) | SMYD2BACE1CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL4122339 | 0.74 | BACE1 (0.38) | SMYD2BACE1CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL4122343 | 0.74 | BACE1 (0.38) | SMYD2BACE1CYP3A4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4646197-A2 | ORGANIC COMPOUNDS AS NLRP3 INHIBITORS | Kodiak Sciences Inc. (US) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024148029-A2 | ORGANIC COMPOUNDS AS NLRP3 INHIBITORS | KODIAK SCIENCES INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148029-A2 | ORGANIC COMPOUNDS AS NLRP3 INHIBITORS | KODIAK SCIENCES INC. (US) | 2024-07-11 | — | — | WO | disclosed |