SCHEMBL29308404

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21083997	0.93	NAE1 (0.55)	NAE1AGTR2CYP3A4ADORA3ADRA2B
	SCHEMBL21083523	0.88	NAE1 (0.52)	NAE1AGTR2CYP3A4ADORA3ADRA2B
	SCHEMBL3977106	0.87	AGTR2 (0.62)	NAE1AGTR2CYP3A4ADORA3ADRA2B
	SCHEMBL7018017	0.84	PPARG (0.59)	NAE1AGTR2CYP3A4ADORA3ADRA2B
	SCHEMBL30206864	0.84	PPARG (0.59)	NAE1AGTR2CYP3A4ADORA3ADRA2B
	SCHEMBL21168140	0.84	AGTR2 (0.59)	NAE1AGTR2CYP3A4ADORA3ADRA2B
	SCHEMBL21083933	0.83	AGTR2 (0.58)	NAE1AGTR2CYP3A4ADORA3ADRA2B
	SCHEMBL7018921	0.83	AGTR2 (0.58)	NAE1AGTR2CYP3A4ADORA3ADRA2B
	SCHEMBL30849999	0.83	AGTR2 (0.58)	NAE1AGTR2CYP3A4ADORA3ADRA2B
	SCHEMBL13465074	0.82	AGTR2 (0.59)	NAE1AGTR2CYP3A4ADORA3ADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.