SCHEMBL2931053

SCHEMBL2931053

CC(=O)Nc1c(B(O)O)cccc1[N+](=O)[O-]

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.49
POLB P06746 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
KCNMA1 Q12791 1/20 0.44
PKM P14618 1/20 0.44
TDP1 Q9NUW8 3/20 0.43
HTT P42858 1/20 0.42
GPR35 Q9HC97 1/20 0.42
ERN1 O75460 1/20 0.41
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
THRB P10828 1/20 0.41
TSHR P16473 1/20 0.41
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9185883 0.87 KMT2A (0.56) KMT2AMEN1POLBSMN1; SMN2L3MBTL1
SCHEMBL29757979 0.82 TGM2 (0.46) KMT2AMEN1POLBSMN1; SMN2L3MBTL1
SCHEMBL30388557 0.81 KCNMA1 (0.63) KMT2AMEN1POLBSMN1; SMN2L3MBTL1
SCHEMBL249599 0.81 KCNMA1 (0.56) KMT2AMEN1POLBSMN1; SMN2L3MBTL1
SCHEMBL5144247 0.81 KCNMA1 (0.63) KMT2AMEN1POLBSMN1; SMN2L3MBTL1
SCHEMBL505372 0.79 KCNMA1 (0.51) KMT2AMEN1POLBSMN1; SMN2L3MBTL1
SCHEMBL9872830 0.79 MEN1 (0.50) KMT2AMEN1POLBSMN1; SMN2L3MBTL1
SCHEMBL601548 0.79 KMT2A (0.50) KMT2AMEN1POLBSMN1; SMN2L3MBTL1
SCHEMBL3412286 0.79 MEN1 (0.50) KMT2AMEN1POLBSMN1; SMN2L3MBTL1
SCHEMBL30625900 0.79 KMT2A (0.50) KMT2AMEN1POLBSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1730102-B1 A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3 , 4,4'-TETRAMINOBIPHENYL COUNCIL SCIENT IND RES (IN) 2010-09-22 EP claimed
EP-1730102-A1 A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3 , 4,4'-TETRAMINOBIPHENYL Council of Scientific and Industrial Research (IN) 2006-12-13 EP claimed
US-6979749-B2 Catalytic process for the production of 3,3′, 4,4′-tetraminobiphenyl COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-12-27 US claimed
WO-2005092839-A1 A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-10-06 WO claimed
US-20050215823-A1 NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-09-29 US claimed
EP-1730102-B1 A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3 , 4,4'-TETRAMINOBIPHENYL COUNCIL SCIENT IND RES (IN) 2010-09-22 EP disclosed
EP-1730102-A1 A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3 , 4,4'-TETRAMINOBIPHENYL Council of Scientific and Industrial Research (IN) 2006-12-13 EP disclosed
US-6979749-B2 Catalytic process for the production of 3,3′, 4,4′-tetraminobiphenyl COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-12-27 US disclosed
WO-2005092839-A1 A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-10-06 WO disclosed
US-20050215823-A1 NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050215823-A1 NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL NNMT, CBR3, POR KMT2A 130/4885MEN1 2108/4885POLB 723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.