Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 3/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29310734 | 0.94 | GAA (0.41) | GAASMN1; SMN2HTTNPC1ALDH1A1 | |
| SCHEMBL21082480 | 0.81 | KDM4E (0.42) | GAASMN1; SMN2HTTNPC1ALDH1A1 | |
| SCHEMBL10595642 | 0.78 | ALDH1A1 (0.36) | SMN1; SMN2HTTALDH1A1TSHRHPGD | |
| SCHEMBL10593961 | 0.78 | ALDH1A1 (0.36) | SMN1; SMN2HTTALDH1A1TSHRHPGD | |
| SCHEMBL1839193 | 0.78 | MAPT (0.35) | GAASMN1; SMN2HTTNPC1ALDH1A1 | |
| SCHEMBL1841005 | 0.78 | MAPT (0.35) | GAASMN1; SMN2HTTNPC1ALDH1A1 | |
| SCHEMBL1841006 | 0.78 | MAPT (0.35) | GAASMN1; SMN2HTTNPC1ALDH1A1 | |
| SCHEMBL1839195 | 0.78 | MAPT (0.35) | GAASMN1; SMN2HTTNPC1ALDH1A1 | |
| SCHEMBL21082414 | 0.77 | POLB (0.38) | GAASMN1; SMN2HTTNPC1ALDH1A1 | |
| SCHEMBL8762317 | 0.76 | ALDH1A1 (0.36) | ALDH1A1TSHRLMNACYP1A2FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226320-A1 | DRUG CONJUGATES WITH SELF-STABILIZING LINKERS HAVING IMPROVED PHYSIOCHEMICAL PROPERTIES | SEAGEN INC (US) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226320-A1 | DRUG CONJUGATES WITH SELF-STABILIZING LINKERS HAVING IMPROVED PHYSIOCHEMICAL PROPERTIES | CD44, CD47, UACA | GAA 233/4885SMN1; SMN2 452/4885HTT 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.