Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 7/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 6/20 | 0.32 |
| ▸ | TGM2 | P21980 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10593961 | 1.00 | ALDH1A1 (0.36) | ALDH1A1TSHRCYP1A2CYP2C19MAPK1 | |
| SCHEMBL8762317 | 0.98 | ALDH1A1 (0.36) | ALDH1A1TSHRCYP1A2MAPK1TDP1 | |
| SCHEMBL20839648 | 0.90 | TSHR (0.36) | ALDH1A1TSHRMAPK1TDP1TGM2 | |
| SCHEMBL21393151 | 0.82 | TSHR (0.33) | ALDH1A1TSHRMAPK1TDP1SMN1; SMN2 | |
| SCHEMBL23870439 | 0.81 | ALDH1A1 (0.37) | ALDH1A1TSHRCYP2C19MAPK1TDP1 | |
| SCHEMBL23870433 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPK1TDP1FABP4 | |
| SCHEMBL29310737 | 0.78 | GAA (0.43) | ALDH1A1TSHRCYP1A2CYP2C19FABP4 | |
| SCHEMBL5105077 | 0.77 | ALDH1A1 (0.34) | ALDH1A1CYP1A2CYP2C19FABP4FABP5 | |
| SCHEMBL7751502 | 0.77 | TSHR (0.38) | ALDH1A1TSHRMAPK1TDP1TGM2 | |
| SCHEMBL10808711 | 0.76 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP2C19FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32952-E | ONE-POT; REACTING KETONE, AMMONIUM SALT, CYANIDE SALT; ACRYLOYLATION, HYDROLYSIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-06-13 | — | — | US | claimed |
| EP-0246849-A1 | Method of preparing N-acryloyl-alpha-amino acids | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-11-25 | — | — | EP | claimed |
| US-4694103-A | Method of preparing N-acryloyl-α-amino acids | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-09-15 | — | — | US | claimed |
| US-RE32952-E | ONE-POT; REACTING KETONE, AMMONIUM SALT, CYANIDE SALT; ACRYLOYLATION, HYDROLYSIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0246849-A1 | Method of preparing N-acryloyl-alpha-amino acids | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-11-25 | — | — | EP | disclosed |
| US-4694103-A | Method of preparing N-acryloyl-α-amino acids | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-09-15 | — | — | US | disclosed |