Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 16/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25082075 | 0.78 | GLS (0.54) | GLS | |
| SCHEMBL30278799 | 0.78 | GLS (0.54) | GLS | |
| SCHEMBL30278820 | 0.78 | GLS (0.54) | GLS | |
| SCHEMBL25319219 | 0.76 | GABRA1 (0.38) | GRIN2BGSK3BDYRK1A | |
| SCHEMBL31150452 | 0.76 | GABRA1 (0.38) | GRIN2BGSK3BDYRK1A | |
| SCHEMBL26822131 | 0.74 | GLS (0.43) | GLS | |
| SCHEMBL24824441 | 0.74 | GLS (0.43) | GLS | |
| SCHEMBL30672258 | 0.74 | GLS (0.43) | GLS | |
| SCHEMBL30672289 | 0.73 | GLS (0.42) | GLS | |
| SCHEMBL26822836 | 0.73 | GLS (0.42) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024141443-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS SIK MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-07-04 | — | — | WO | disclosed |