Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 4/20 | 0.43 |
| ▸ | NPY2R | P49146 | 3/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.42 |
| ▸ | INSR | P06213 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | MC1R | Q01726 | 1/20 | 0.41 |
| ▸ | PRLHR | P49683 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.40 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.40 |
| ▸ | VEGFA | P15692 | 2/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29311858 | 0.97 | KCNA3 (0.43) | APLNRNPY2RCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL29311547 | 0.97 | CSNK2A2 (0.43) | APLNRNPY2RCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL29311757 | 0.97 | CSNK2A2 (0.43) | APLNRNPY2RCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL26307010 | 0.93 | NPY2R (0.48) | NPY2RCSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL29311576 | 0.92 | VEGFA (0.44) | CSNK2A2CSNK2BCSNK2A1CSNK2A3INSR | |
| SCHEMBL29311793 | 0.91 | KCNA3 (0.43) | APLNRNPY2RCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL26292602 | 0.91 | RAMP3 (0.49) | NPY2RCSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL29311773 | 0.91 | CXCR4 (0.41) | CSNK2A2CSNK2BCSNK2A1CSNK2A3INSR | |
| SCHEMBL26292620 | 0.89 | RAMP3 (0.47) | CSNK2A2CSNK2BCSNK2A1CSNK2A3CTNNB1 | |
| SCHEMBL26292629 | 0.89 | RAMP3 (0.47) | CSNK2A2CSNK2BCSNK2A1CSNK2A3CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226225-A1 | CONJUGATED HEPCIDIN MIMETICS | PROTAGONIST THERAPEUTICS, INC. (US) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226225-A1 | CONJUGATED HEPCIDIN MIMETICS | HAMP, SLC40A1, FTH1 | APLNR 28/4885NPY2R 1641/4885CSNK2A2 4835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.