Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 5/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31406505 | 0.90 | PLA2G2A (0.54) | PLA2G2ATSHRTP53ALOX15NR5A1 | |
| SCHEMBL31406517 | 0.90 | PLA2G2A (0.54) | PLA2G2ATSHRTP53ALOX15NR5A1 | |
| SCHEMBL11694989 | 0.90 | PLA2G2A (0.54) | PLA2G2ATSHRTP53ALOX15NR5A1 | |
| SCHEMBL5090331 | 0.90 | PLA2G2A (0.54) | PLA2G2ATSHRTP53ALOX15NR5A1 | |
| SCHEMBL13836862 | 0.90 | PLA2G2A (0.54) | PLA2G2ATSHRTP53ALOX15NR5A1 | |
| SCHEMBL5090437 | 0.90 | PLA2G2A (0.54) | PLA2G2ATSHRTP53ALOX15NR5A1 | |
| SCHEMBL31406472 | 0.90 | PLA2G2A (0.54) | PLA2G2ATSHRTP53ALOX15NR5A1 | |
| SCHEMBL5088868 | 0.90 | PLA2G2A (0.54) | PLA2G2ATSHRTP53ALOX15NR5A1 | |
| SCHEMBL5095048 | 0.90 | PLA2G2A (0.54) | PLA2G2ATSHRTP53ALOX15NR5A1 | |
| SCHEMBL8641708 | 0.86 | NR5A1 (0.49) | PLA2G2ATSHRTP53ALOX15NR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228433-A1 | COMPOUNDS AND METHODS FOR LIQUID PHASE OLIGONUCLEOTIDE SYNTHESIS | HONGENE BIOTECH CORPORATION | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228433-A1 | COMPOUNDS AND METHODS FOR LIQUID PHASE OLIGONUCLEOTIDE SYNTHESIS | POLR2H, POLRMT, POLR2E | PLA2G2A 1952/4885TSHR 2927/4885TP53 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.