SCHEMBL29313140

SCHEMBL29313140

COC1C(COP(=O)(O)OP(O)(=S)OP(=O)(O)OCC2OC(N3CN(C)c4c3nc(N)[nH]c4=O)C(OC)C2O)OC(n2cnc3c(=O)[nH]c(N)nc32)C1O

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.56
FUT5 Q11128 1/20 0.54
NT5E P21589 1/20 0.52
KRAS P01116 7/20 0.52
P2RY2 P41231 1/20 0.51
P2RY4 P51582 1/20 0.51
P2RY6 Q15077 1/20 0.51
DCPS Q96C86 1/20 0.50
TAS1R3 Q7RTX0 1/20 0.47
TAS1R1 Q7RTX1 1/20 0.47
P2RY1 P47900 1/20 0.46
P2RY11 Q96G91 1/20 0.46
IMPDH2 P12268 1/20 0.46
IMPDH1 P20839 1/20 0.46
P2RX3 P56373 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24051592 0.97 TGM2 (0.60) TGM2FUT5NT5EKRASP2RY2
SCHEMBL18769124 0.93 TGM2 (0.63) TGM2FUT5NT5EKRASP2RY2
SCHEMBL29313147 0.93 FUT5 (0.58) TGM2FUT5NT5EKRASP2RY2
SCHEMBL18769061 0.89 FUT5 (0.55) TGM2FUT5NT5EKRASP2RY2
SCHEMBL18769127 0.87 TGM2 (0.60) TGM2FUT5NT5EKRASP2RY2
SCHEMBL18763211 0.87 FUT5 (0.68) TGM2FUT5NT5EKRASP2RY2
SCHEMBL18769134 0.86 TGM2 (0.54) TGM2FUT5NT5EKRASP2RY2
SCHEMBL22388612 0.86 FUT5 (0.58) TGM2FUT5NT5EKRASP2RY2
SCHEMBL18769157 0.85 TGM2 (0.54) TGM2FUT5NT5EKRASP2RY2
SCHEMBL18769060 0.85 TGM2 (0.69) TGM2FUT5NT5EKRASP2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226132-A1 RNA COMPOSITIONS COMPRISING A BUFFER SUBSTANCE AND METHODS FOR PREPARING, STORING AND USING THE SAME BIONTECH DELIVERY TECHNOLOGIES GMBH (DE) 2024-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226132-A1 RNA COMPOSITIONS COMPRISING A BUFFER SUBSTANCE AND METHODS FOR PREPARING, STORING AND USING THE SAME SNRPB2, NSUN2, RNMT TGM2 3338/4885FUT5 2732/4885NT5E 514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.