SCHEMBL29313467

SCHEMBL29313467

CC[C@H]1O[C@@H](n2ccc3c(NC(=O)c4ccccc4)ncnc32)[C@H](O)[C@@H]1C

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 3/20 0.53
▸ METTL3 Q86U44 1/20 0.44
▸ METTL14 Q9HCE5 1/20 0.44
▸ PRMT5 O14744 2/20 0.44
▸ WDR77 Q9BQA1 2/20 0.44
▸ SLC29A1 Q99808 1/20 0.43
▸ ADORA3 P0DMS8 1/20 0.43
▸ ADORA1 P30542 1/20 0.43
▸ BMPR1B O00238 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29313461 0.93 ADK (0.60) ADKMETTL3METTL14PRMT5WDR77
SCHEMBL27103047 0.88 ADK (0.50) ADKMETTL3METTL14PRMT5WDR77
SCHEMBL29313494 0.86 BMPR1B (0.56) SLC29A1ADORA3ADORA1BMPR1B
SCHEMBL24687181 0.86 ADK (0.72) ADKMETTL3METTL14SLC29A1ADORA3
SCHEMBL23023836 0.86 ADK (0.72) ADKMETTL3METTL14SLC29A1ADORA3
SCHEMBL31123791 0.86 ADK (0.72) ADKMETTL3METTL14SLC29A1ADORA3
SCHEMBL31228160 0.85 ADK (0.60) ADKMETTL3METTL14PRMT5WDR77
SCHEMBL26298193 0.83 ADK (0.45) ADKMETTL3METTL14PRMT5WDR77
SCHEMBL31167393 0.81 ADK (0.60) ADKMETTL3METTL14SLC29A1
SCHEMBL25410585 0.81 ADK (0.60) ADKMETTL3METTL14SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12036231-B2 Cyclic dinucleotides as agonists of stimulator of interferon gene dependent signalling BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-07-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12036231-B2 Cyclic dinucleotides as agonists of stimulator of interferon gene dependent signalling STING1, IRF3, CGAS ADK 370/4885METTL3 4785/4885METTL14 4707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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