Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482011 | 0.85 | CYP11B2 (0.41) | CYP11B2 | |
| SCHEMBL481935 | 0.76 | CYP11B2 (0.40) | CYP11B2 | |
| SCHEMBL481912 | 0.76 | MAP4K4 (0.33) | — | |
| SCHEMBL481911 | 0.76 | MAP4K4 (0.33) | — | |
| SCHEMBL481577 | 0.71 | MCHR1 (0.39) | CYP11B2 | |
| SCHEMBL21827579 | 0.67 | CDK2 (0.36) | CYP11B2 | |
| SCHEMBL31035734 | 0.64 | FEN1 (0.38) | — | |
| SCHEMBL21312554 | 0.64 | NFE2L2 (0.38) | CYP11B2CTSDBACE1BACE2 | |
| SCHEMBL14120336 | 0.63 | — | — | |
| SCHEMBL21826803 | 0.63 | CDK2 (0.39) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |