Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 9/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313462 | 0.86 | LRRK2 (0.39) | AURKACHEK1LRRK2SYKPRKCQ | |
| SCHEMBL29313773 | 0.81 | CCNA2 (0.46) | AURKALRRK2CDK1KDRSYK | |
| SCHEMBL18293973 | 0.79 | PRKCQ (0.56) | CHEK1PRKCQPRKCD | |
| SCHEMBL16842117 | 0.77 | PRKCQ (0.63) | PRKCQPRKCD | |
| SCHEMBL29313606 | 0.73 | PTK2 (0.40) | AURKALRRK2SYKPRKCQ | |
| SCHEMBL23019347 | 0.73 | PRKCQ (0.41) | AURKALRRK2SYKPRKCQ | |
| SCHEMBL29315063 | 0.73 | LRRK2 (0.35) | AURKALRRK2CDK1KDRSYK | |
| SCHEMBL4770519 | 0.71 | AURKA (0.46) | AURKACHEK1LRRK2CDK1KDR | |
| SCHEMBL29313552 | 0.71 | PTK2 (0.43) | AURKALRRK2SYKPRKCQPRKCD | |
| SCHEMBL29314061 | 0.70 | PDE4A (0.39) | AURKALRRK2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782986-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-10 | — | — | EP | disclosed |