Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 4/20 | 0.46 |
| ▸ | CDK2 | P24941 | 4/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314042 | 0.81 | NUDT1 (0.45) | AURKASYKLRRK2CDK1KDR | |
| SCHEMBL29313462 | 0.80 | LRRK2 (0.39) | AURKASYKLRRK2PRKCQ | |
| SCHEMBL27502303 | 0.79 | CSNK1A1 (0.51) | CCNA2CDK2CCNA1EGFRAURKA | |
| SCHEMBL29313606 | 0.77 | PTK2 (0.40) | EGFRAURKASIRT5SYKKDM4E | |
| SCHEMBL23019347 | 0.77 | PRKCQ (0.41) | AURKASYKLRRK2PRKCQ | |
| SCHEMBL4772582 | 0.76 | AURKA (0.52) | CCNA2CDK2CCNA1AURKASYK | |
| SCHEMBL29313552 | 0.75 | PTK2 (0.43) | EGFRAURKASYKLRRK2PRKCQ | |
| SCHEMBL29314061 | 0.74 | PDE4A (0.39) | CCNA2CDK2CCNA1AURKASYK | |
| SCHEMBL29315097 | 0.73 | MAP3K8 (0.43) | AURKAFLT3SIRT5SYKLRRK2 | |
| SCHEMBL29313537 | 0.73 | PTK2 (0.56) | SYKKDM4EALDH1A1HTTKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782986-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-10 | — | — | EP | disclosed |