Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK3 | P49761 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 6/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313537 | 0.84 | PTK2 (0.56) | PTK2PTK2BSYKKDM4EGAA | |
| SCHEMBL29313552 | 0.81 | PTK2 (0.43) | PTK2PTK2BSYKAURKAPRKCQ | |
| SCHEMBL29313542 | 0.81 | ALDH1A1 (0.54) | CLK4SIRT5KDM4EPGK1 | |
| SCHEMBL29313615 | 0.80 | VNN1 (0.47) | PTK2PTK2BSYKAURKASIRT5 | |
| SCHEMBL29315097 | 0.79 | MAP3K8 (0.43) | PTK2PTK2BSYKAURKASIRT5 | |
| SCHEMBL29313621 | 0.78 | PTK2 (0.41) | PTK2PTK2BSYKAURKASIRT5 | |
| SCHEMBL29315070 | 0.78 | MAP3K8 (0.45) | PTK2PTK2BCLK2CLK4SYK | |
| SCHEMBL29313773 | 0.77 | CCNA2 (0.46) | SYKAURKASIRT5KDM4EPRKCQ | |
| SCHEMBL29315063 | 0.75 | LRRK2 (0.35) | SYKAURKASIRT5PRKCQLRRK2 | |
| SCHEMBL29314042 | 0.73 | NUDT1 (0.45) | SYKAURKAPRKCQLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782986-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-10 | — | — | EP | disclosed |