Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 13/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313773 | 0.77 | CCNA2 (0.46) | PRKCQAURKALRRK2SYK | |
| SCHEMBL29314061 | 0.74 | PDE4A (0.39) | AURKALRRK2SYK | |
| SCHEMBL29314042 | 0.73 | NUDT1 (0.45) | PRKCQAURKALRRK2SYK | |
| SCHEMBL29313606 | 0.72 | PTK2 (0.40) | PRKCQAURKALRRK2SYK | |
| SCHEMBL29313462 | 0.72 | LRRK2 (0.39) | PRKCQAURKALRRK2SYK | |
| SCHEMBL29313569 | 0.72 | TNK2 (0.48) | — | |
| SCHEMBL29314449 | 0.71 | CHEK1 (0.49) | PRKCQLRRK2SYK | |
| SCHEMBL29313552 | 0.70 | PTK2 (0.43) | PRKCQAURKALRRK2SYK | |
| SCHEMBL20164739 | 0.68 | SLC29A1 (0.40) | — | |
| SCHEMBL23782214 | 0.68 | CNR2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782986-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2021-02-24 | — | — | EP | disclosed |