Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5021082 | 0.89 | LRRK2 (0.40) | ALDH1A1LRRK2TDP1LMNAMAPK1 | |
| SCHEMBL5421688 | 0.84 | ALDH1A1 (0.39) | ALDH1A1CDK9DYRK1ADYRK2TLR7 | |
| SCHEMBL17076702 | 0.81 | MPO (0.36) | ALDH1A1CDK9DYRK1ADYRK2TLR7 | |
| SCHEMBL17076654 | 0.81 | ALDH1A1 (0.34) | ALDH1A1CDK9DYRK1ADYRK2TLR7 | |
| SCHEMBL15652073 | 0.80 | POLB (0.40) | ALDH1A1KMT2APOLB | |
| SCHEMBL5418741 | 0.79 | ALDH1A1 (0.35) | ALDH1A1TLR7TDP1LMNAHPGD | |
| SCHEMBL14445363 | 0.79 | ALDH1A1 (0.36) | ALDH1A1TLR7LRRK2TDP1LMNA | |
| SCHEMBL14445349 | 0.78 | ALDH1A1 (0.34) | ALDH1A1TLR7TDP1LMNAHPGD | |
| SCHEMBL5423811 | 0.78 | ALDH1A1 (0.34) | ALDH1A1TLR7TDP1LMNAHPGD | |
| SCHEMBL14958720 | 0.77 | TLR8 (0.39) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146923-A1 | TUBULIN POLYMERIZATION INHIBITORS | AB SCIENCE (FR) | 2024-07-11 | — | — | WO | disclosed |