Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31299886 | 0.85 | KDM4E (0.42) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL3125411 | 0.82 | MEN1 (0.41) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL1104456 | 0.81 | CYP3A4 (0.45) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL29400731 | 0.81 | CYP3A4 (0.45) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL11619402 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPTSETDB1 | |
| SCHEMBL24252949 | 0.73 | THRB (0.45) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL13154151 | 0.72 | THRB (0.42) | ALDH1A1SMN1; SMN2THRBHPGDMAOB | |
| SCHEMBL9871803 | 0.72 | KDM4E (0.44) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL10141739 | 0.72 | PTGDR2 (0.46) | ALDH1A1HTTMAPTSETDB1CYP1A2 | |
| SCHEMBL596184 | 0.69 | CYP3A4 (0.50) | ALDH1A1HTTMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226104-A1 | PI3K INHIBITORS, NANOFORMULATIONS, AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226104-A1 | PI3K INHIBITORS, NANOFORMULATIONS, AND USES THEREOF | PI4KA, PIK3CA, PI4KB | ALDH1A1 3641/4885HTT 1878/4885MEN1 3531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.