Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | IAPP | P10997 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2325202 | 0.85 | GPR52 (0.38) | LMNATSHRSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL5693066 | 0.85 | L3MBTL1 (0.47) | TDP1L3MBTL1PTGS2ALDH1A1HPGD | |
| SCHEMBL13105884 | 0.84 | GABRA1 (0.46) | THRBMAOBLMNATSHRSMN1; SMN2 | |
| SCHEMBL2876253 | 0.80 | CA12 (0.48) | LMNATSHRSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL27733110 | 0.80 | ALDH1A1 (0.34) | LMNATSHRTDP1L3MBTL1PTGS2 | |
| SCHEMBL4830107 | 0.80 | L3MBTL1 (0.37) | LMNATSHRTDP1L3MBTL1PTGS2 | |
| SCHEMBL28360772 | 0.80 | CA12 (0.37) | THRBMAOBLMNATSHRTDP1 | |
| SCHEMBL27453547 | 0.79 | ALDH1A1 (0.45) | THRBMAOBIAPPLMNASMN1; SMN2 | |
| SCHEMBL5693160 | 0.79 | CA12 (0.56) | LMNATSHRSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL696352 | 0.79 | THRB (0.56) | THRBLMNATSHRSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803950-B2 | Method for the production of diarylcycloalkyl derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-09-28 | — | — | US | disclosed |
| US-20080051583-A1 | NOVEL INTERMEDIATE COMPOUNDS USEFUL IN THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-02-28 | — | — | US | disclosed |
| US-20070197614-A1 | METHOD FOR THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051583-A1 | NOVEL INTERMEDIATE COMPOUNDS USEFUL IN THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | PPARG, PPARD, PPARA | THRB 1836/4885MAOB 624/4885IAPP 1042/4885 |
| US-20070197614-A1 | METHOD FOR THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | PPARA, PPARD, PPARG | THRB 987/4885MAOB 573/4885IAPP 1300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.