Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314187 | 0.90 | MAPT (0.33) | POLQRXFP1MAPT | |
| SCHEMBL29314174 | 0.85 | POLQ (0.33) | POLQ | |
| SCHEMBL29314178 | 0.76 | POLQ (0.33) | POLQ | |
| SCHEMBL29313704 | 0.71 | POLQ (0.39) | POLQRXFP1MAPT | |
| SCHEMBL29313698 | 0.70 | POLQ (0.37) | POLQ | |
| SCHEMBL29314177 | 0.68 | POLQ (0.31) | POLQ | |
| SCHEMBL29313802 | 0.66 | POLQ (0.34) | POLQ | |
| SCHEMBL30847690 | 0.66 | PER2 (0.35) | POLQ | |
| SCHEMBL29313701 | 0.65 | POLQ (0.37) | POLQRXFP1MAPT | |
| SCHEMBL29313751 | 0.62 | POLQ (0.39) | POLQRXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |