Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 10/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | MST1R | Q04912 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22109643 | 0.84 | ATR (0.40) | MET | |
| SCHEMBL29314335 | 0.84 | MET (0.35) | METHDAC3PDE10A | |
| SCHEMBL22109644 | 0.83 | ABCB1 (0.36) | METBRAFHDAC3 | |
| SCHEMBL21167537 | 0.82 | MET (0.38) | METBRAFHDAC3MAP4K4PDE10A | |
| SCHEMBL21167659 | 0.82 | MAP4K4 (0.43) | METBRAFHDAC3MAP4K4PDE10A | |
| SCHEMBL21167741 | 0.80 | MET (0.39) | METHDAC3MAP4K4PDE10APDK1 | |
| SCHEMBL14378443 | 0.79 | MET (0.44) | METHDAC3PDE10APDK1CHKA | |
| SCHEMBL22109506 | 0.78 | MET (0.40) | METHDAC3PDE10APDK1CHKA | |
| SCHEMBL21167662 | 0.78 | MET (0.37) | METKDRHDAC3PDE10APDK1 | |
| SCHEMBL22109501 | 0.76 | MET (0.40) | METHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |