Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 18/20 | 0.39 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29317092 | 0.86 | MET (0.43) | ATRMET | |
| SCHEMBL29314758 | 0.86 | ATR (0.34) | ATRMETCDKL5 | |
| SCHEMBL29314335 | 0.86 | MET (0.35) | MET | |
| SCHEMBL29317374 | 0.84 | MET (0.42) | ATRMET | |
| SCHEMBL29317202 | 0.84 | ATR (0.41) | ATRMETCDKL5 | |
| SCHEMBL22109645 | 0.84 | KDM1A (0.33) | METCDKL5 | |
| SCHEMBL22109644 | 0.84 | ABCB1 (0.36) | MET | |
| SCHEMBL29314345 | 0.84 | MET (0.34) | MET | |
| SCHEMBL22109501 | 0.82 | MET (0.40) | ATRMET | |
| SCHEMBL29315094 | 0.82 | ATR (0.40) | ATRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |
| WO-2020124060-A1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA, INC. (US) | 2020-06-18 | — | — | WO | disclosed |