Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 15/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314289 | 0.86 | MET (0.37) | METPDE10AKLKB1KLK1HDAC3 | |
| SCHEMBL22109643 | 0.86 | ATR (0.40) | MET | |
| SCHEMBL22109644 | 0.84 | ABCB1 (0.36) | METKLKB1KLK1HDAC3 | |
| SCHEMBL29314345 | 0.84 | MET (0.34) | METPDE10AHDAC3 | |
| SCHEMBL22109506 | 0.80 | MET (0.40) | METPDE10AKLKB1KLK1HDAC3 | |
| SCHEMBL22109501 | 0.77 | MET (0.40) | METHDAC3 | |
| SCHEMBL29314519 | 0.76 | ABCB1 (0.33) | METKLKB1KLK1HDAC3 | |
| SCHEMBL29317092 | 0.75 | MET (0.43) | MET | |
| SCHEMBL29316038 | 0.74 | MET (0.36) | METKLKB1KLK1 | |
| SCHEMBL29317374 | 0.73 | MET (0.42) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |