Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2398779 | 0.79 | MRGPRX4 (0.40) | NOTUMALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL2397684 | 0.76 | CYP1A2 (0.41) | ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL20431211 | 0.74 | — | — | |
| SCHEMBL19826317 | 0.74 | CCNE2 (0.31) | — | |
| SCHEMBL17544561 | 0.72 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL7612576 | 0.69 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL16635596 | 0.69 | TRPA1 (0.42) | NOTUMALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL16516129 | 0.68 | MRGPRX4 (0.42) | NOTUMALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL2497965 | 0.66 | ALDH1A1 (0.47) | NOTUMALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL4327362 | 0.64 | ALDH1A1 (0.51) | NOTUMALDH1A1CYP1A2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400172-A2 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | Incyte Holdings Corporation (US) | 2024-07-17 | — | — | EP | disclosed |