Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | PRF1 | P14222 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4198688 | 0.80 | ALDH1A1 (0.69) | ALDH1A1CYP3A4CA2PRF1NPC1 | |
| SCHEMBL11314892 | 0.76 | ALDH1A1 (0.58) | ALDH1A1CYP3A4CA2PRF1NPC1 | |
| SCHEMBL713413 | 0.76 | ALDH1A1 (0.62) | ALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL132773 | 0.75 | ALDH1A1 (0.78) | ALDH1A1CYP3A4CA2IDH1 | |
| SCHEMBL9687590 | 0.74 | ALDH1A1 (0.60) | ALDH1A1CYP3A4CA2NPC1RAB9A | |
| SCHEMBL9686517 | 0.74 | ALDH1A1 (0.60) | ALDH1A1CYP3A4CA2NPC1RAB9A | |
| SCHEMBL12518683 | 0.74 | ALDH1A1 (0.60) | ALDH1A1CYP3A4CA2ERN1PRF1 | |
| SCHEMBL487227 | 0.74 | ALDH1A1 (0.78) | ALDH1A1NPC1RAB9ANAAA | |
| SCHEMBL3082528 | 0.74 | ALDH1A1 (0.60) | ALDH1A1CYP3A4CA2RAB9AIDH1 | |
| SCHEMBL10604973 | 0.73 | ALDH1A1 (0.69) | ALDH1A1CYP3A4CA2IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915399-B1 | RECOVERABLE POLYMER-BOUND HOMOGENEOUS CATALYSTS FOR CATALYTIC CHAIN TRANSFER PROCESSES | COATINGS FOREIGN IP CO LLC (US) | 2013-11-20 | — | — | EP | disclosed |
| US-8030422-B2 | Recoverable polymer-bound homogeneous catalysts for catalytic chain transfer process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-10-04 | — | — | US | disclosed |
| US-20100261851-A1 | Recoverable polymer-bound homogeneous catalysts for catalytic chain transfer process | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2010-10-14 | — | — | US | disclosed |
| EP-1915399-A1 | RECOVERABLE POLYMER-BOUND HOMOGENEOUS CATALYSTS FOR CATALYTIC CHAIN TRANSFER PROCESSES | E.I.Du pont de nemours and company (US) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007024634-A1 | RECOVERABLE POLYMER-BOUND HOMOGENEOUS CATALYSTS FOR CATALYTIC CHAIN TRANSFER PROCESSES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-03-01 | — | — | WO | disclosed |