Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.53 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2935037 | 0.89 | MAPK14 (0.47) | NPSR1CYP1A2CYP2C9CYP2C19CSNK1E | |
| SCHEMBL2929905 | 0.86 | L3MBTL1 (0.47) | NPSR1CYP1A2CYP2C9CYP2C19CSNK1E | |
| SCHEMBL2929605 | 0.86 | MAPK14 (0.41) | NPSR1CYP1A2CYP2C9CYP2C19CSNK1E | |
| SCHEMBL4051659 | 0.84 | LMNA (0.43) | NPSR1CYP1A2CYP2C9CYP2C19CSNK1E | |
| SCHEMBL13498508 | 0.77 | NPSR1 (0.69) | NPSR1CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL2926388 | 0.76 | MAPK14 (0.53) | NPSR1CSNK1EKDM4EL3MBTL1MAPK1 | |
| SCHEMBL1384932 | 0.74 | ADORA2A (0.45) | NPSR1CSNK1EKDM4EL3MBTL1MAPK1 | |
| SCHEMBL2934339 | 0.73 | MAPK14 (0.41) | NPSR1KDM4EL3MBTL1MAPK1LMNA | |
| SCHEMBL2834708 | 0.73 | NPSR1 (0.68) | NPSR1CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL1939380 | 0.73 | NPSR1 (0.68) | NPSR1CYP1A2CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611131-B1 | PYRAZOLOPYRIDINE DERIVATES | PALAU PHARMA SA (ES) | 2010-09-15 | — | — | EP | disclosed |
| CN-100354275-C | Pyrazolopyridine derivates | URIACH Y COMPAGNIA S A J (ES) | 2007-12-12 | — | — | CN | disclosed |
| CN-1753894-A | Pyrazolopyridine derivates | URIACH Y COMPAGNIA S A J (ES) | 2006-03-29 | — | — | CN | disclosed |