Sugi Predict

Sugi Predict / Compounds / SCHEMBL29314448

SCHEMBL29314448

SCHEMBL29314448

CCCCNC[Si](C)(C)O[Si](C)(C)CNCCCN

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CASP2 P42575 2/20 0.39
▸ CA12 O43570 2/20 0.39
▸ F13A1 P00488 2/20 0.39
▸ CA2 P00918 2/20 0.39
▸ CYP1A2 P05177 2/20 0.39
▸ ALOX15 P16050 2/20 0.39
▸ CA4 P22748 2/20 0.39
▸ CA6 P23280 2/20 0.39
▸ CA5A P35218 2/20 0.39
▸ THPO P40225 2/20 0.39
▸ CA7 P43166 2/20 0.39
▸ CA9 Q16790 2/20 0.39
▸ CA14 Q9ULX7 2/20 0.39
▸ CA5B Q9Y2D0 2/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ TSHR P16473 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29314419 0.84 CA12 (0.36) CA12CA2ALOX15CA4CA6
SCHEMBL2428717 0.83 CA12 (0.43) CASP2CA12F13A1CA2CYP1A2
SCHEMBL29314423 0.81 CA12 (0.42) CASP2CA12F13A1CA2CYP1A2
SCHEMBL29314583 0.79 CA12 (0.50) CASP2CA12F13A1CA2CYP1A2
SCHEMBL197913 0.76 — —
SCHEMBL21496029 0.75 TSHR (0.44) CA12CA2ALOX15CA7CA14
SCHEMBL15170563 0.74 CA12 (0.39) CASP2CA12CA2ALOX15CA4
SCHEMBL17931060 0.74 CASP2 (0.72) CASP2CA12F13A1CA2CYP1A2
Hydrochloric Acid SCHEMBL9343695 0.74 UBE2N (0.68) CASP2CA12F13A1CA2CYP1A2
SCHEMBL8190944 0.74 CA12 (0.63) CASP2CA12F13A1CA2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239819-A1 SYNTHESIS OF AMINOALKYL-SUBSTITUTED DISILOXANES GE INFRASTRUCTURE TECHNOLOGY LLC 2024-07-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239819-A1 SYNTHESIS OF AMINOALKYL-SUBSTITUTED DISILOXANES SRM, DAO, SMOX CASP2 1615/4885CA12 4214/4885F13A1 1842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.