Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 16/20 | 0.34 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22109643 | 0.86 | ATR (0.40) | ATRMETCDKL5 | |
| SCHEMBL29314697 | 0.77 | MET (0.37) | ATRMETKCNH2HRH3 | |
| SCHEMBL29317202 | 0.76 | ATR (0.41) | ATRMETCDKL5KCNH2 | |
| SCHEMBL29317092 | 0.76 | MET (0.43) | ATRMET | |
| SCHEMBL29317374 | 0.75 | MET (0.42) | ATRMET | |
| SCHEMBL22109501 | 0.74 | MET (0.40) | ATRMET | |
| SCHEMBL22109389 | 0.74 | MET (0.40) | ATRMET | |
| SCHEMBL29314335 | 0.73 | MET (0.35) | METKCNH2 | |
| SCHEMBL29317084 | 0.72 | MET (0.43) | ATRMET | |
| SCHEMBL22109644 | 0.72 | ABCB1 (0.36) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |