Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 9/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | LDHB | P07195 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314697 | 0.90 | MET (0.37) | METATRLDHALDHBKCNH2 | |
| SCHEMBL29317374 | 0.83 | MET (0.42) | METATR | |
| SCHEMBL14378355 | 0.76 | ATR (0.44) | METATRLDHALDHB | |
| SCHEMBL29317092 | 0.76 | MET (0.43) | METATR | |
| SCHEMBL22109643 | 0.73 | ATR (0.40) | METATR | |
| SCHEMBL22109389 | 0.72 | MET (0.40) | METATR | |
| SCHEMBL29317084 | 0.72 | MET (0.43) | METATRHPGD | |
| SCHEMBL29316038 | 0.72 | MET (0.36) | METCHKA | |
| SCHEMBL29314758 | 0.72 | ATR (0.34) | METATRKCNH2HRH3 | |
| SCHEMBL22109506 | 0.72 | MET (0.40) | METCHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |